Gout and Pseudogout are polygenic autoinflammatory diseases and are called Crystal Induced Arthritis (CIA). Read: Autoinflammatory Diseases WHAT IS GOUT It is an auto-inflammatory disease where the innate immune system responds excessively to uric acid (monosodium urate – MSU) crystals. Gout mainly manifests as a joint disease (urate crystals deposit in joints, triggering autoinflammation). Risk



